Effects of Aerobic Exercise on Brain Age and Health in Middle-Aged and Older Adults: A Single-Arm Pilot Clinical Trial.
An OuyangCan Martin ZhangNoor AdraRyan A TeshHaoqi SunDan LeiJin JingPeng FanLuis PaixaoWolfgang GanglbergerLogan BriggsJoel SalinasMatthew B BeversChristiane Dorothea WrannZeina ChemaliGregory L FricchioneRobert J ThomasJonathan RosandRudolph E TanziMichael Brandon WestoverPublished in: Life (Basel, Switzerland) (2024)
max) and plasma cytokine profiles. However, we found no measurable effects on sleep architecture or BAI. It remains to be seen whether a study with a larger sample size and more intensive or more prolonged exercise exposure can demonstrate a beneficial effect on sleep quality and brain age.
Keyphrases
- sleep quality
- physical activity
- clinical trial
- resting state
- depressive symptoms
- white matter
- public health
- functional connectivity
- healthcare
- study protocol
- cerebral ischemia
- mental health
- multiple sclerosis
- phase ii
- blood brain barrier
- resistance training
- risk assessment
- phase iii
- human health
- subarachnoid hemorrhage