Simvastatin-Nicotinamide Co-Crystals: Formation, Pharmaceutical Characterization and in vivo Profile.
Fahad Mehmood KhanMahmood AhmadHafiz Arfat IdreesPublished in: Drug design, development and therapy (2020)
Co-crystallization with NIC improved the solubility and dissolution profile and, hence, the bioavailability of the poorly water-soluble drug SIM.