Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort.

Kate BramhamPia M VillaJennifer R JoslinHannele LaivuoriEsa HämäläinenEero KajantieKatri RäikkönenAnukatriina PesonenPaul T SeedR Neil DaltonCharles TurnerMax WongPeter Von DadelszenJames M RobertsLucilla PostonLucy C Chappell

Published in: Hypertension in pregnancy (2020)

Decreased syndecan-1 and PlGF concentrations implicate endothelial glycocalyx disturbance and reduced placental angiogenic capacity, respectively, in the pathophysiology of superimposed preeclampsia.

Keyphrases

early onset
endothelial cells
blood pressure
pregnancy outcomes
left ventricular
heart failure
pregnant women