Body mass index and leptin are related to cognitive performance over 10 years in women with and without HIV infection.
Francesca MacalusoKathleen M WeberLeah H RubinElaine DellingerSusan HolmanHoward MinkoffSheila KeatingLisa R MerlinDeborah R GustafsonPublished in: The Journal of clinical endocrinology and metabolism (2021)
In middle-aged WIHS participants, 10-year increases in BMI and leptin were associated with poorer performance across multiple NP domains among all and WWH. Trajectories of adiposity measures over time may provide insight into the role of adipose tissue in brain health with aging.
Keyphrases
- middle aged
- adipose tissue
- insulin resistance
- healthcare
- public health
- weight gain
- body mass index
- depressive symptoms
- resting state
- mental health
- white matter
- antiretroviral therapy
- high fat diet
- health information
- functional connectivity
- metabolic syndrome
- cerebral ischemia
- health promotion
- skeletal muscle
- multiple sclerosis
- risk assessment
- physical activity
- climate change
- blood brain barrier