HSP22 (HSPB8) positively regulates PGF2α-induced synthesis of interleukin-6 and vascular endothelial growth factor in osteoblasts.
Gen KuroyanagiGo SakaiTakanobu OtsukaNaohiro YamamotoKazuhiko FujitaTetsu KawabataRie Matsushima-NishiwakiOsamu KozawaHaruhiko TokudaPublished in: Journal of orthopaedic surgery and research (2021)
Our results strongly suggest that HSP22 acts as a positive regulator in the PGF2α-induced synthesis of IL-6 and VEGF in osteoblasts.