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HSP22 (HSPB8) positively regulates PGF2α-induced synthesis of interleukin-6 and vascular endothelial growth factor in osteoblasts.

Gen KuroyanagiGo SakaiTakanobu OtsukaNaohiro YamamotoKazuhiko FujitaTetsu KawabataRie Matsushima-NishiwakiOsamu KozawaHaruhiko Tokuda
Published in: Journal of orthopaedic surgery and research (2021)
Our results strongly suggest that HSP22 acts as a positive regulator in the PGF2α-induced synthesis of IL-6 and VEGF in osteoblasts.
Keyphrases
  • vascular endothelial growth factor
  • heat shock protein
  • high glucose
  • endothelial cells
  • heat shock
  • diabetic rats
  • drug induced
  • transcription factor
  • oxidative stress
  • stress induced