Serum Alpha-synuclein in Restless Legs Syndrome.
Aboud TahanisVera HashemWilliam G OndoPublished in: Sleep (2024)
In our study of 113 RLS subjects, serum α-syn levels were decreased in RLS patients compared to healthy controls and increased in the 9 patients who received IV iron treatment in correlation with ferritin. This correlation could suggest a mechanism for reduced dopamine transmission in RLS.