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Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for drug repositioning.

Hon Cheong SoCarlos Kwan-Long ChauAlexandria LauSze-Yung WongKai Zhao
Published in: Psychological medicine (2018)
Taken together, our findings suggest that human genomic data such as GWAS are useful in guiding drug discoveries for depression and AD.
Keyphrases
  • endothelial cells
  • genome wide
  • adverse drug
  • mental health
  • drug induced
  • depressive symptoms
  • dna methylation
  • sleep quality
  • deep learning
  • transcription factor
  • artificial intelligence