Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness.
Karan SeegobinMuhamad Alhaj MoustafaDeborah FischerKatelyn KellerJacquelyn HastingsMohamed A Kharfan-DabajaErnesto AyalaVivek GuptaHan W TunLiuyan JiangPublished in: Clinical case reports (2020)
ALK-positive ALCL can lead to rapid irreversible destruction of the optic pathway. Early treatment should be instituted in patients with CNS involvement or those at increased CNS risk.