Metabolic syndrome traits differentially and cumulatively influence micro- and macrovascular disease risk in patients with MASLD.

Alex E Henney David R Riley Theresa J HydesMatthew AnsonGema H IbarburuSizheng S ZhaoDaniel J CuthbertsonUazman Alam

Published in: Liver international : official journal of the International Association for the Study of the Liver (2024)

We demonstrate a differential effect of MetS components on micro- and macrovascular disease risk in patients with MASLD, with a cumulative impact of multiple MetS on overall risk. The impact of MetS components was most pronounced in women. Aggressive metabolic risk factor management is critical for prevention of micro- and macrovascular complications.

Keyphrases

metabolic syndrome
risk factors
type diabetes
polycystic ovary syndrome
insulin resistance
adipose tissue
pregnant women
dna methylation
breast cancer risk
pregnancy outcomes
cervical cancer screening