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Inhibition of Staphylococcus aureus Efflux Pump by O-Eugenol and Its Toxicity in Drosophila melanogaster Animal Model.

Nair Silva MacêdoZildene de Sousa SilveiraPaula Patrícia Marques CordeiroHenrique Doouglas Melo CoutinhoJosé Pinto Siqueira JúniorLucindo José Quintans JúniorAbolghasem SiyadatpanahBonlgee KimFrancisco Assis Bezerra da CunhaMárcia Vanusa da Silva
Published in: BioMed research international (2022)
While we can conclude that the tested product has an efflux pump inhibitory effect, further studies are needed to elucidate its mechanisms of action, in addition to assays using other strains to verify whether the substance has the same inhibitory effect.
Keyphrases
  • staphylococcus aureus
  • drosophila melanogaster
  • escherichia coli
  • oxidative stress
  • high throughput
  • biofilm formation
  • cystic fibrosis
  • case control