Representativeness of samples enrolled in Alzheimer's disease research centers.
Miguel Arce RenteríaTaylor M MobleyNicole D EvangelistaLuis D MedinaKacie D DetersJoshua T Fox-FullerLex R MintoJustina Avila-RiegerBrianne M BettcherPublished in: Alzheimer's & dementia (Amsterdam, Netherlands) (2023)
We examined selection factors included in NACC studies compared to a nationally representative sample.Selection factors included demographic and health factors and self-reported memory concerns.Results suggest that NACC participants are not representative of the U.S. population.Importantly, selection factors differed across racial and ethnic groups.Findings are suggestive of selection bias within NACC studies.