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Anti-KIF20B autoantibodies are associated with cranial neuropathy in systemic lupus erythematosus.

Eugene KrustevJohn G HanlyRicky ChinKatherine A BuhlerMurray B UrowitzCaroline GordonSang-Cheol BaeJuanita Romero-DiazJorge Sánchez-GuerreroSasha BernatskyDaniel J WallaceDavid IsenbergAnisur RahmanJoan T MerrillPaul R FortinDafna D GladmanIan N BruceMichelle A PetriEllen M GinzlerMary Anne DooleyRosalind Ramsey-GoldmanSusan ManziAndreas JönsenGraciela S AlarcónRonald F Van VollenhovenCynthia AranowMeggan MackayGuillermo Ruiz-IrastorzaSung Sam LimMurat InancKenneth C KalunianSøren JacobsenChristine A PeschkenDiane L KamenAnca AskenaseJill BuyonMarvin J FritzlerAnn E ClarkeMay Yee Choi
Published in: Lupus science & medicine (2024)
Anti-KIF20B is a potential biomarker for SLE-related CN. Further studies are needed to examine how autoantibodies against KIF20B, which is variably expressed in a variety of neurological cells, contribute to disease pathogenesis.
Keyphrases
  • systemic lupus erythematosus
  • induced apoptosis
  • disease activity
  • cell cycle arrest
  • lymph node metastasis
  • squamous cell carcinoma
  • signaling pathway
  • cell death
  • brain injury
  • blood brain barrier