Effect of Cladribine on Neuronal Apoptosis: New Insight of In Vitro Study in Multiple Sclerosis Therapy.

Maddalena RuggieriConcetta Domenica GarganoFerretta AnnaAlessia ManniAntonio CapacchioneAntonio FrigeriPietro IaffaldanoMaria TrojanoDamiano Paolicelli

Published in: Brain sciences (2020)

2-CdA causes peripheral and central lymphocyte death preserving neurons, with a reasonable impact on inflammation and neuroprotection.

Keyphrases

multiple sclerosis
oxidative stress
cerebral ischemia
endoplasmic reticulum stress
spinal cord
cell death
brain injury
peripheral blood
white matter
replacement therapy