Low-grade uterine Leiomyosarcoma is highly sensitive to hormonal treatment.

Roberta Sanfilippo Marta Sbaraglia Chiara Fabbroni Sabrina Croce Isabelle L Ray-Coquard Fatma Valentina Guermazi Biagio Paolini Félix Blanc-Durand Axel Le Cesne Valentina Chiappa Angelo Paolo Dei Tos Paolo Giovanni Casali

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

We observed a response or long-term stability rate on hormonal therapy in the 90% range; in all cases the time to relapse was significantly longer than in ULMS and in most cases the relapse was abdominal. Based on these findings, we conclude that a proportion of patients with uterine smooth muscle neoplasms actually present with a "low-grade ULMS".

Keyphrases

low grade
smooth muscle
high grade
polycystic ovary syndrome
free survival
metabolic syndrome
molecularly imprinted
high resolution