Inhibiting of GRASP65 Phosphorylation by DL-3-N-Butylphthalide Protects against Cerebral Ischemia-Reperfusion Injury via ERK Signaling.

Bei-Lei ZhuChen-Long XieNing-Ning HuXin-Bo Zhu Chun-Feng Liu

Published in: Behavioural neurology (2018)

The current finding suggested that NBP protected the cerebrum from CIRI mediated by inhibiting the ERK signaling pathway and subsequently reducing GRASP65 phosphorylation.

Keyphrases

signaling pathway
ischemia reperfusion injury
pi k akt
induced apoptosis
epithelial mesenchymal transition
protein kinase
oxidative stress
subarachnoid hemorrhage
cerebral blood flow