Dynamic brainstem and somatosensory cortical excitability during migraine cycles.
Fu-Jung HsiaoWei-Ta ChenLi-Ling Hope PanHung-Yu LiuYen-Feng WangShih-Pin ChenKuan-Lin LaiGianluca CoppolaShuu-Jiun WangPublished in: The journal of headache and pain (2022)
This study demonstrates that migraine is a cyclic excitatory disorder and that the neural substrates involved include the somatosensory system, starting in the brainstem and spanning subsequently to the S1 before the migraine occurs. Further investigations with larger sample sizes are warranted.