Acute hospitalizations after proton therapy versus intensity-modulated radiotherapy for locally advanced non-small cell lung cancer in the durvalumab era.
Michelle IocolanoNikhil Yegya-RamanCole FriedesXingmei WangTimothy KegelmanSang Ho LeeLian DuanBolin LiWilliam P LevinKeith A CengelAndre KonskiCorey J LangerRoger B CohenLova SunCharu AggarwalAbigail DoucetteYing XiaoBoon-Keng Kevin TeoShannon O'ReillyWei ZouJeffrey D BradleyCharles B Simone IiSteven J FeigenbergPublished in: Cancer (2024)
PBT is associated with fewer unplanned hospitalizations, lower effective dose to immune circulating cells and less G3+ lymphopenia compared with IMRT. Minimizing dose to lymphocytes may be warranted, but prospective data are needed.
Keyphrases
- induced apoptosis
- liver failure
- cell cycle arrest
- early stage
- electronic health record
- respiratory failure
- peripheral blood
- locally advanced
- big data
- endoplasmic reticulum stress
- drug induced
- radiation induced
- squamous cell carcinoma
- intensive care unit
- machine learning
- cell proliferation
- hepatitis b virus
- artificial intelligence