The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis.

Antonia Fh SmeltJacobijn GusseklooLynette W BerminghamElizabeth AllenAlan D DangourSimone Jpm EussenBernard FavratLisette C P G M de GrootFrans J KokTimothy KwokArduino A MangoniGeorge NtaiosOndine Van De RestEric SealPaul VaucherPetra VerhoefTheo StijnenWendy Pj Den Elzen

Published in: European journal of clinical nutrition (2018)

Evidence on the effects of supplementation of low concentrations of vitamin B12 and folate on haematological parameters in community-dwelling older people is inconclusive. Further research is needed before firm recommendations can be made concerning the supplementation of vitamin B12 and folate.

Keyphrases

community dwelling
systematic review
clinical practice
meta analyses
electronic health record
big data
case control