β-Amyloid in blood neuronal-derived extracellular vesicles is elevated in cognitively normal adults at risk of Alzheimer's disease and predicts cerebral amyloidosis.

Tao-Ran LiYun-Xia YaoXue-Yan JiangQiu-Yue DongXian-Feng YuTing WangYan-Ning CaiYing Han

Published in: Alzheimer's research & therapy (2022)

levels in diagnosing AD-induced cognitive impairment and Aβ+ NCs. This biomarker reflects cortical amyloid deposition and predicts cognitive decline and entorhinal atrophy.

Keyphrases

cognitive decline
mild cognitive impairment
cognitive impairment
high glucose
cerebral ischemia
diabetic rats
subarachnoid hemorrhage
multiple myeloma
oxidative stress
endothelial cells
brain injury