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Prediction of worsening heart failure in hypertrophic cardiomyopathy using plasma proteomics.

Heidi S LumishLusha W LiangKohei HasegawaMathew S MaurerMichael A FiferMuredach P ReillyYuichi J Shimada
Published in: Heart (British Cardiac Society) (2023)
The present study with comprehensive plasma proteomics profiling demonstrated a high accuracy to predict worsening HF in patients with HCM and identified the Ras-MAPK and related signalling pathways as potential underlying mechanisms.
Keyphrases
  • hypertrophic cardiomyopathy
  • left ventricular
  • heart failure
  • mass spectrometry
  • signaling pathway
  • acute heart failure
  • label free
  • single cell
  • cell proliferation