Low cytomegalovirus seroprevalence in early multiple sclerosis: a case for the 'hygiene hypothesis'?

E Alari-PahissaA MoreiraA ZabalzaR Alvarez-LafuenteE MunteisA VeraR ArroyoJ C Alvarez-CermeñoLuisa Maria VillarM López-BotetJose E Martínez-Rodríguez

Published in: European journal of neurology (2018)

Low CMV seroprevalence was observed in patients with early MS. Modification of MS risk attributed to CMV might be related to the induction of differentiated T-cell and NK-cell subsets and/or modulation of Epstein-Barr virus-specific immune responses at early stages of the disease.

Keyphrases

epstein barr virus
multiple sclerosis
immune response
mass spectrometry
diffuse large b cell lymphoma
ms ms
white matter