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Phyto-Engineered Gold Nanoparticles (AuNPs) with Potential Antibacterial, Antioxidant, and Wound Healing Activities Under in vitro and in vivo Conditions.

Pandi BoomiRamalingam GanesanGurumallesh Prabu PooraniSonamuthu JegatheeswaranChandrasekaran BalakumarHalliah Gurumallesh PrabuKrishnan AnandNarayanasamy Marimuthu PrabhuJeyaraman JeyakanthanMuthupandian Saravanan
Published in: International journal of nanomedicine (2020)
The pharmacological evaluation results of the study indicated an encouraging antibacterial and antioxidant activity of the greener synthesized gold nanoparticles tethered with aqueous extract of Acalypha indica. Moreover, we demonstrated enhanced in vivo wound-healing efficiency of the synthesized gold nanoparticles through the animal model. Thus, the outcome of this work revealed that the phyto-engineered gold nanoparticles could be useful for biomedical applications, especially in the development of promising antibacterial and wound-healing agents.
Keyphrases
  • gold nanoparticles
  • wound healing
  • reduced graphene oxide
  • anti inflammatory
  • oxidative stress
  • single cell
  • climate change