Decreased plasma kallikrein activity is associated with reduced kidney function in individuals with type 1 diabetes.
Mari-Anne HärmaEmma H DahlströmNiina SandholmCarol ForsblomPer-Henrik GroopMarkku Lehtonull nullPublished in: Diabetologia (2020)
Plasma kallikrein activity and genetic variants known to increase the plasma kallikrein level are associated with higher eGFR in individuals with type 1 diabetes, suggesting that plasma kallikrein might have a protective effect in diabetic nephropathy.