Dehydroepiandrosterone modulates oxidative DNA damage in pancreatic cancer: A case-control study.

Hamid Reza FazliAshraf MohamadkhaniHamed Reza GodarziAkram PourshamsMojtaba Jafari Nia

Published in: JGH open : an open access journal of gastroenterology and hepatology (2021)

These results indicate that serum DHEA reduces the risk of pancreatic cancer with an anti-DNA damage effect. Hence, the influence of DHEA to prohibit the accumulation of 8-OHdG may be one of its physiological functions.

Keyphrases

dna damage
dna repair
oxidative stress