Blue Mussel (Mytilus edulis) Water Extract Ameliorates Inflammatory Responses and Oxidative Stress on Osteoarthritis in Obese Rats.
Heng-Wei ChangSabri SudirmanYu-Wen YenChien-Feng MaoAlan Darmasaputra OngZwe-Ling KongPublished in: Journal of pain research (2020)
MWE suppressed proinflammatory mediators and attenuated the cartilage degradation and pain in osteoarthritis rats under obesity condition. Therefore, MWE has the potential to act as an alternative for osteoarthritis treatment.
Keyphrases
- oxidative stress
- rheumatoid arthritis
- knee osteoarthritis
- weight loss
- metabolic syndrome
- type diabetes
- insulin resistance
- chronic pain
- adipose tissue
- pain management
- weight gain
- neuropathic pain
- bariatric surgery
- ischemia reperfusion injury
- skeletal muscle
- body mass index
- induced apoptosis
- signaling pathway
- obese patients
- anti inflammatory
- replacement therapy
- smoking cessation
- heat shock