A study on the correlation between M2 macrophages and regulatory T cells in the progression of colorectal cancer.

Yanlei ChenYu GaoXueqian MaYanping WangJinhao LiuChunyu YangYue WangCuifen BaoXiaoyu SongYang FengYan SunShifeng Qiao

Published in: The International journal of biological markers (2022)

CD163 may be a good predictor of pre-metastatic status of colorectal cancer lymph nodes. carcinoembryonic antigen affects the distribution of M2 macrophages and Tregs in colorectal cancer. There is a certain correlation between the two types of cells. It is possible that M2 macrophages, together with suppressor Tregs cells, promote an immunosuppressive environment.

Keyphrases

regulatory t cells
induced apoptosis
lymph node
cell cycle arrest
small cell lung cancer
squamous cell carcinoma
dendritic cells
endoplasmic reticulum stress
cell death
signaling pathway
oxidative stress
early stage
pi k akt
sentinel lymph node