Exploring the Overlap Between Alopecia Areata and Major Depressive Disorder: Epidemiological and Genetic Perspectives.

Jerome Clifford FooS RedlerA J ForstnerF B BasmanavL PethukovaJia GuoF StreitS H WittL SirignanoL ZillichS AvasthiS RipkeA M ChristianoF TeschJ SchmittM M NöthenRegina C BetzM RietschelJ Frank

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)

As in previous research, AA patients showed an increased prevalence of MDD. The present analyses suggest that genetic overlap may be confined to the MHC region, which is implicated in immune function. More detailed investigation is required to refine understanding of how the MHC is involved in the development of AA and MDD comorbidity.

Keyphrases

major depressive disorder
bipolar disorder
end stage renal disease
ejection fraction
genome wide
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
copy number
patient reported outcomes