Clinical influence of switching companion diagnostic tests for EGFR-TKs from Therascreen to Cobas v2.

Ken UchiboriNatsuki TakanoRyo ManabeRyosuke TsugitomiShinsuke OgusuTakehiro TozukaHiroaki SakamotoHiroshi YoshidaYoshiaki AminoRyo AriyasuSatoru KitazonoNoriko YanagitaniMakoto Nishio

Published in: Thoracic cancer (2021)

Switching CDx tests from target polymerase chain reaction (PCR)- to next-generation sequencing (NGS)-based methods may lead to obvious changes in clinical practice. When the CDx test is required to change, the investigation of this influence is warranted in future studies.

Keyphrases

clinical practice
small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
copy number
current status
gene expression
genome wide