Does high-dose benzodiazepine abuse really produce liver toxicity? Results from a series of 201 benzodiazepine monoabusers.

Fabio Lugoboni Antonio MirijelloLaura MorbioliElena ArzentonRoberto LeoneMarco FacciniRebecca CasariSalvatore De Cosmo Antonio Gasbarrini Giovanni Addolorato

Published in: Expert opinion on drug safety (2018)

Present data suggest that prolonged use of high-dose BZD, although very dangerous for several reasons, does not seem to produce a significant drug-induced liver injury.

Keyphrases

high dose
stem cell transplantation
low dose
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oxidative stress
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adverse drug
data analysis