High- Versus Low-Molecular-Weight Hyaluronic Acid for the Treatment of Rotator Cuff Tendinopathy: A Triple-Blind Randomized Comparative Trial.

Rezvaneh MohebbiZahra RezasoltaniMahshad MirMaryam MohebbiSima VatandoostHadi Esmaily

Published in: The Annals of pharmacotherapy (2021)

Both medications are effective for the treatment of tendinopathy. The benefits last at least for 3 months, and pain alleviation lasts partially for 6 months. The shoulder injection of LMW hyaluronate is more tolerable to the patient. Therefore, we recommend LMW hyaluronate as the first choice for the management of rotator cuff tendinopathy.

Keyphrases

rotator cuff
hyaluronic acid
phase iii
phase ii
chronic pain
clinical trial
open label
double blind
pain management
study protocol
platelet rich plasma
neuropathic pain
spinal cord
placebo controlled
decision making