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Automated quantitative MRI volumetry reports support diagnostic interpretation in dementia: a multi-rater, clinical accuracy study.

Hugh G PembertonOlivia GoodkinFerran PradosRavi K DasSjoerd B VosJames MoggridgeWilliam CoathElizabeth GordonRyan BarrettAnne SchmittHefina Whiteley-JonesChristian BurdMike P WattjesSven HallerMeike W VernooijLorna HarperNick C FoxRoss W PatersonJonathan M SchottSotirios BisdasMark WhiteSebastien OurselinJohn S ThorntonTarek A YousryM Jorge CardosoFrederik Barkhofnull null
Published in: European radiology (2021)
• The use of quantitative report alongside routine visual MRI assessment improves sensitivity and accuracy for detecting volume loss and AD vs visual assessment alone. • Consultant neuroradiologists' assessment accuracy and agreement (kappa scores) significantly improved with the use of quantitative atrophy reports. • First multi-rater radiological clinical evaluation of visual quantitative MRI atrophy report for use as a diagnostic aid in dementia.
Keyphrases
  • contrast enhanced
  • magnetic resonance imaging
  • high resolution
  • mild cognitive impairment
  • diffusion weighted imaging
  • high throughput
  • deep learning
  • computed tomography
  • machine learning
  • nuclear factor
  • single cell