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Role of interleukin-6 and interleukin-10 in morphological and functional changes of the blood-brain barrier in hypertriglyceridemia.

Beáta BarabásiLilla BarnaAna Raquel Santa-MariaAndrás HarazinRéka MolnárAndrás KincsesJudit P VighBrigitta DukayMiklós SánthaMelinda E TóthFruzsina R WalterMária A DeliZsófia Hoyk
Published in: Fluids and barriers of the CNS (2023)
IL-6 produced in microvessels contributes to BBB impairment observed in the APOB-100 mice. We showed that IL-10 partly antagonizes the effects of IL-6 at the BBB.
Keyphrases
  • blood brain barrier
  • type diabetes
  • metabolic syndrome
  • insulin resistance