Synaptic Protein Loss in Extracellular Vesicles Reflects Brain and Retinal Atrophy in People With Multiple Sclerosis.
Dimitrios Christos LadakisMichael VreonesJoseph BlommerKimystian L HarrisonMatthew D SmithEleni S VasileiouHussein MoussaGelareh AhmadiOmar EzzedinAnna L DuValBlake E DeweyJerry L PrinceKathryn C FitzgeraldElias S SotirchosShiv SaidhaPeter A CalabresiDimitrios KapogiannisPavan BhargavaPublished in: Neurology(R) neuroimmunology & neuroinflammation (2024)
NEV-derived synaptic proteins likely reflect neurodegeneration and may provide additional circulating biomarkers for disease progression in MS.