Prenatal exome sequencing and impact on perinatal outcome: cohort study.

B PoljakU AgarwalZ AlfirevicS AllenN CanhamJ HiggsA Kaelin AgtenAsma KhalilD RobertsFionnuala MoneK Navaratnam

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2022)

This study demonstrates the potential impact of causative variants identified by pES on decisions for late TOP. As the R21 pathway continues to evolve we urge clinicians and policymakers to consider earlier screening for anomalies, develop robust guidance for late TOP and ensure optimized support for couples. This article is protected by copyright. All rights reserved.

Keyphrases

pregnant women
copy number
palliative care
gene expression
risk assessment
climate change