The change in circulating tumor cells before and during concurrent chemoradiotherapy is associated with survival in patients with locally advanced head and neck cancer.
Hung-Ming WangMin-Hsien WuPei-Hung ChangHung-Chi LinChun-Da LiaoSheng-Min WuTsung-Min HungChien-Yu LinTung-Chieh ChangTzu-Chen YenJason Chia-Hsun HsiehPublished in: Head & neck (2019)
In chemoradiotherapy responders, CTCs are significantly reduced. CTC decline within the first month indicates a longer PFS and OS, suggesting that the dynamics of CTCs could be more important than CTC number alone.