Recent Recall of Iron Reagent-Investigation of Potential Reagent Contamination and Assay Improvement Strategy.
Madhusudhanan NarasimhanKefyalew JaletaShishir AdhikariMizanu BerihunKavithalakshmi SataraNatarajanLenin MahimainathanJing CaoPatricia Mary JonesIbrahim HashimAlagar R MuthukumarPublished in: The journal of applied laboratory medicine (2024)
We conclude that accidental copper contamination of R2 reagent during manufacturing could be a reason underlying the positive bias in the recalled iron reagent lots. Addition of TU in ferene-containing R2 reagent is a simple and effective means to prevent Cu-induced false elevation in iron values.