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Recent Recall of Iron Reagent-Investigation of Potential Reagent Contamination and Assay Improvement Strategy.

Madhusudhanan NarasimhanKefyalew JaletaShishir AdhikariMizanu BerihunKavithalakshmi SataraNatarajanLenin MahimainathanJing CaoPatricia Mary JonesIbrahim HashimAlagar R Muthukumar
Published in: The journal of applied laboratory medicine (2024)
We conclude that accidental copper contamination of R2 reagent during manufacturing could be a reason underlying the positive bias in the recalled iron reagent lots. Addition of TU in ferene-containing R2 reagent is a simple and effective means to prevent Cu-induced false elevation in iron values.
Keyphrases
  • risk assessment
  • drinking water
  • human health
  • iron deficiency
  • health risk
  • high throughput
  • high glucose
  • heavy metals
  • drug induced
  • endothelial cells