Novel Long-Acting Drug Combination Nanoparticles Composed of Gemcitabine and Paclitaxel Enhance Localization of Both Drugs in Metastatic Breast Cancer Nodules.
Jesse YuQingxin MuSimone PerazzoloJames I GriffinLinxi ZhuLisa A McConnachieDanny D ShenRodney J Y HoPublished in: Pharmaceutical research (2020)
DcNPs can deliver hydrophilic G and hydrophobic T together to cancer nodules and produce long acting exposure, likely due to stable GT association to DcNPs in vivo.