New Insights into the Effects of SARS-CoV-2 on Metabolic Organs: A Narrative Review of COVID-19 Induced Diabetes.
Lu LiLin LiXianhui CaiZongfu PanPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2024)
Coronavirus disease 2019 (COVID-19)-induced new-onset diabetes has raised widespread concerns. Increased glucose concentration and insulin resistance levels were observed in the COVID-19 patients. COVID-19 patients with newly diagnosed diabetes may have worse clinical outcomes and can have serious consequences. The types and exact mechanisms of COVID-19-caused diabetes are not well understood. Understanding the direct effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on pancreatic beta cells and insulin target metabolism organs, such as the liver, muscle, and adipose tissues, will provide new ideas for preventing and treating the new-onset diabetes induced by COVID-19.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- coronavirus disease
- type diabetes
- glycemic control
- cardiovascular disease
- insulin resistance
- adipose tissue
- newly diagnosed
- blood glucose
- high glucose
- metabolic syndrome
- skeletal muscle
- gene expression
- blood pressure
- high fat diet
- induced apoptosis
- cell proliferation
- oxidative stress