Emerging Materials, Wearables, and Diagnostic Advancements in Therapeutic Treatment of Brain Diseases.
Brindha RamasubramanianVundrala Sumedha ReddyVijila ChellappanSeeram RamakrishnaPublished in: Biosensors (2022)
Among the most critical health issues, brain illnesses, such as neurodegenerative conditions and tumors, lower quality of life and have a significant economic impact. Implantable technology and nano-drug carriers have enormous promise for cerebral brain activity sensing and regulated therapeutic application in the treatment and detection of brain illnesses. Flexible materials are chosen for implantable devices because they help reduce biomechanical mismatch between the implanted device and brain tissue. Additionally, implanted biodegradable devices might lessen any autoimmune negative effects. The onerous subsequent operation for removing the implanted device is further lessened with biodegradability. This review expands on current developments in diagnostic technologies such as magnetic resonance imaging, computed tomography, mass spectroscopy, infrared spectroscopy, angiography, and electroencephalogram while providing an overview of prevalent brain diseases. As far as we are aware, there hasn't been a single review article that addresses all the prevalent brain illnesses. The reviewer also looks into the prospects for the future and offers suggestions for the direction of future developments in the treatment of brain diseases.
Keyphrases
- resting state
- white matter
- computed tomography
- magnetic resonance imaging
- functional connectivity
- cerebral ischemia
- healthcare
- emergency department
- multiple sclerosis
- drug delivery
- current status
- machine learning
- risk assessment
- positron emission tomography
- high resolution
- subarachnoid hemorrhage
- combination therapy
- single molecule
- blood brain barrier
- sensitive detection
- replacement therapy
- electronic health record
- real time pcr
- dual energy