The Protective Role of Toll-Like Receptor Agonist Monophosphoryl Lipid A Against Vaccinated Murine Schistosomiasis.

Ibrahim AlyEssam H IbrahimRabab S HamadHoda E L SayedSama M N AttiyahWafaa E-KomyHamed A GhramhAli AlshehriKhalid M AlsyaadMohammed AlshehriMona KilanyKareem MorsyAttalla F El-KottRamadan Taha

Published in: Acta parasitologica (2020)

Treatment with MPLA has multi-functions in attenuating the deleterious impacts of S. mansoni infection in mice livers. Its effects are mediated through a reduction of ova count, worm burden, granuloma diameter and amelioration of antioxidant defense systems, and liver function biomarkers.

Keyphrases

toll like receptor
nuclear factor
inflammatory response
immune response
oxidative stress
high fat diet induced
type diabetes
risk factors
peripheral blood
optic nerve
combination therapy
anti inflammatory
adipose tissue
optical coherence tomography