2'-Hydroxycinnamaldehyde Alleviates Intestinal Inflammation by Attenuating Intestinal Mucosal Barrier Damage Via Directly Inhibiting STAT3.

Meilin ChenShuchun WeiXiaohan WuZixuan XiangXiangyun LiHaodong HeFei LiaoXiaoli WangJixiang ZhangBaoping YuWeiguo Dong

Published in: Inflammatory bowel diseases (2024)

We present a novel finding that HCA reduces colitis severity by attenuating intestinal mucosal barrier damage via STAT3. This discovery holds promise as a potential new strategy to alleviate UC.

Keyphrases

oxidative stress
ulcerative colitis
cell proliferation
small molecule
signaling pathway
high throughput
risk assessment
climate change