Incidence and outcomes of adverse drug reactions to first-line anti-tuberculosis drugs and their effects on the quality of life: A multicenter prospective cohort study.
Hayoung ChoiHang A ParkIn Gyu HyunJoo-Hee KimYong Il HwangSeung Hun JangYun Su SimTae Rim ShinYousang KoGa Young BanJi-Young HongChang Youl LeeMyung Goo LeeJeong Hee ChoiPublished in: Pharmacoepidemiology and drug safety (2022)
ADRs to first-line anti-TB drugs were common and related to relatively low QoL, especially among older adults. Although 9.5% of patients had ADR-related regimen changes, most patients with ADRs completed treatments successfully.
Keyphrases
- adverse drug
- end stage renal disease
- mycobacterium tuberculosis
- drug induced
- newly diagnosed
- chronic kidney disease
- ejection fraction
- emergency department
- prognostic factors
- risk factors
- peritoneal dialysis
- type diabetes
- clinical trial
- metabolic syndrome
- adipose tissue
- insulin resistance
- skeletal muscle
- antiretroviral therapy
- patient reported