Analytical assay validation for acute myeloid leukemia measurable residual disease assessment by multiparametric flow cytometry.

Jesse Marc TetteroNaveen DakappagariMaaike E HeidingaYvonne Oussoren-BrockhoffDiana HanekampAnil PahujaKerri BurnsPavinder KaurZeni AlfonsoVincent H J van der VeldenJeroen G Te MarveldeWillemijn HoboJennichjen SlompCosta BachasAngele KelderKevin NguyenJacqueline Cloos

Published in: Cytometry. Part B, Clinical cytometry (2023)

In this manuscript, we present the validation of an AML MFC-MRD assay using BM/PB patient specimens, adhering to best practices. Our approach is expected to assist other laboratories in expediting their validation activities to fulfill recent health authority guidelines.

Keyphrases

acute myeloid leukemia
flow cytometry
healthcare
high throughput
public health
primary care
mental health
allogeneic hematopoietic stem cell transplantation
heavy metals
case report
clinical practice
climate change
social media
health promotion