Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes.
Jia-Xi MiaoJia-Ping XuRui WangYu-Xian XuFeng XuChun-Hua WangChao YuDong-Mei ZhangJian-Bin SuPublished in: Diabetology & metabolic syndrome (2024)
Increased trunk fat mass may partly account for decreased insulin sensitivity and increased insulin secretion, while decreased limb lean mass may be connected to increased fasting glucagon and postprandial glucagon secretion.
Keyphrases
- body composition
- type diabetes
- bone mineral density
- resistance training
- blood glucose
- induced apoptosis
- adipose tissue
- insulin resistance
- cell cycle arrest
- glycemic control
- cell proliferation
- metabolic syndrome
- blood pressure
- cell death
- postmenopausal women
- signaling pathway
- high intensity
- lower limb
- weight loss
- pi k akt