Fatal Acinetobacter baumanii Necrotizing Fasciitis following Open Reduction Internal Fixation in a Polytrauma Patient.
Alexandre H NehmeNabih I JoukhadarElias SaidyMohammad DarwicheDany K AouadHicham G Abdel NourPublished in: Case reports in infectious diseases (2018)
Necrotizing fasciitis is an uncommon and potentially fatal infection that can affect the epidermis, dermis, and more commonly the subcutaneous, fascia, and muscle layers. NF is usually caused by toxin-producing bacteria with a relatively fast progression associated with severe surrounding tissue destruction. Early diagnosis and management are crucial factors for survival. Broad-spectrum antibiotics along with surgical debridement, sometimes multiple, are needed in order to stop or slow down the progression of NF. Despite optimal care, necrotizing fasciitis remains a highly morbid condition with a high mortality rate. We present a case of a 28-year-old male patient with rapidly developing fatal A. baumannii associated with necrotizing fasciitis, after open reduction and internal fixation (ORIF) of multiple fractures after polytrauma.
Keyphrases
- signaling pathway
- case report
- minimally invasive
- lps induced
- healthcare
- pi k akt
- escherichia coli
- oxidative stress
- nuclear factor
- bariatric surgery
- skeletal muscle
- palliative care
- cardiovascular events
- risk factors
- quality improvement
- early onset
- cell proliferation
- cardiovascular disease
- type diabetes
- toll like receptor
- cystic fibrosis
- pseudomonas aeruginosa
- acinetobacter baumannii
- weight loss