Lactic acidosis incidence with metformin in patients with type 2 diabetes and chronic kidney disease: A retrospective nested case-control study.
Carlos A AlvarezEthan A HalmMary Jo V PughDarren K McGuireSean HennessyRichard T MillerIldiko LingvayScott Martin VouriAndrew R ZulloHui YangMatt ChansardEric M MortensenPublished in: Endocrinology, diabetes & metabolism (2020)
Metformin was not associated with an elevated risk of LA in persons with stage 1-2 CKD, but was associated with a progressively higher risk at more advanced stages of CKD.