Obstructive Sleep Apnea, Platelet Aggregation, and Cardiovascular Risk.
Zanetta KovbasyukJaime Ramos-CejudoAnkit ParekhOmonigho M BubuIndu A AyappaAndrew W VargaMing-Huei ChenAndrew Danner JohnsonEugenio Gutierrez-JimenezDavid M RapoportRicardo S OsorioPublished in: Journal of the American Heart Association (2024)
No associations were detected between OSA and platelet aggregation in a community sample. Our finding that OSA associates with increased platelet aggregation in the aspirin group, most of whom use it for primary prevention of CVD, suggests that platelet aggregation may mediate the adverse impact of OSA on vascular health in individuals with existing CVD risk, supporting further investigation.