Genetic diversity of Escherichia coli in gut microbiota of patients with Crohn's disease discovered using metagenomic and genomic analyses.
Alexander V TyakhtAlexander I ManolovAlexandra V KanyginaDmitry S IschenkoBoris A KovarskyAnna S PopenkoAlexander V PavlenkoAnna V ElizarovaDaria V RakitinaJulia P BaikovaValentina G LadyginaElena S KostryukovaIrina Y KarpovaTatyana A SemashkoAndrei K LarinTatyana V GrigoryevaMariya N SinyaginaSergei Y MalaninPetr L ShcherbakovAnastasiya Y KharitonovaIgor L KhalifMarina V ShapinaIgor V MaevDmitriy N AndreevElena A BelousovaYulia M BuzunovaDmitry G AlexeevVadim M GovorunPublished in: BMC genomics (2018)
The genomic diversity of Crohn's disease-associated E. coli within and among the patients paves the way towards an understanding of the microbial mechanisms underlying the onset and progression of the Crohn's disease and the development of new strategies for the prevention and treatment of this disease.