Autoimmunity plays a role in the onset of diabetes after 40 years of age.
Olaf RolandssonChristiane S HampeStephen J SharpEva ArdanazHeiner BoeingGuy FagherazziFrancesca Romana ManciniPeter M NilssonKim OvervadMaria-Dolores ChirlaqueMiren DorronsoroMarc J GunterRudolf KaaksTimothy J KeyKay-Tee KhawVittorio KroghTilman KühnDomenico PalliSalvatore PanicoCarlotta SacerdoteMaria-José SánchezGianluca SeveriAnnemieke M W SpijkermanRosario TuminoYvonne T van der SchouwElio RiboliNita G ForouhiClaudia LangenbergNicholas J WarehamPublished in: Diabetologia (2019)
Our study indicates that incident diabetes in adults has an element of autoimmune aetiology. Thus, there might be a reason to re-evaluate the present subclassification of diabetes in adulthood.