Increasing plasma glucose before the development of type 1 diabetes-the TRIGR study.
Johnny LudvigssonDavid CuthbertsonDorothy J BeckerOlga KordonouriBärbel AschemeierDanièle PacaudCheril ClarsonJeffrey P KrischerOlli H Laitinennull nullPublished in: Pediatric diabetes (2021)
A pronounced increase in plasma glucose and HbA1c precedes development of clinical diabetes, while the association between plasma glucose or HbA1c and development of autoantibodies is complex. Increased insulin demand may contribute to development of type 1 diabetes.